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Tagrisso osimertinib
This page contains brief details about the drug osimertinib, it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval for Tagrisso osimertinib
Tagrisso Osimertinib is an anticancer medication that the Food and Drug Administration approved on the 18th of April 2018 as a first-line treatment for patients having non-small cell lung cancer (NSLC), that has spread to other parts and whose tumors have epidermal growth factor receptor (EGFR) mutations.
Later on the 18th of December 2020, Osimertinib got approval for being used as an additional therapy after tumor removed by surgery in patients having metastatic non-small cell lung cancer (NSLC) whose tumors have epidermal growth factor receptor (EGFR) mutations.
Mechanism of Action of Tagrisso Osimertinib
Tagrisso Osimertinib is a targeted therapy medication and belongs to the category of oral EGFR kinase inhibitor. It works by producing inhibitory action on the Epidermal growth factor receptor (EGFR) and retards the growing cancer cells. Osimertinib also works by slowing down or stopping lung cancer from growing and reducing the tumor size. In addition, it also works by preventing the recurrence of the tumor after its removal through surgery.
Available Brands (2 products)
Tagrisso 80mg TabletAstrazeneca Pharma IndiaTagrisso 40mg TabletAstrazeneca Pharma IndiaUses of Osimertinib
Tagrisso Osimertinib is indicated to treat non-small cell lung cancer (NSCLS) in adults. It is also used as a first-line treatment for patients having metastatic non-small cell lung cancer (NSLC) whose tumors have epidermal growth factor receptor (EGFR) mutations. In addition, it is also used after the removal of tumors by surgery.
Tagrisso osimertinib Drug administaration and Dosage available
Osimertinib is an prescription medicine available as a tablet in two doses Osimertinib 40mg and Osimertinib 80mg. This medication is to be taken by mouth and swallowed as a whole with or without food at the same time every day as prescribed by your doctor. It should not be crushed, split, or chewed. If you cannot swallow the tablets, you can dissolve them as per your doctor's advice.
Warnings, Precautions and Side Effects of Osimertinib
Warnings when taking Tagrisso osimertinib
Inform your doctor immediately if you experience difficulty breathing with fever or cough, as it might indicate lung inflammation. Notify your doctor immediately if you have any symptoms like dizziness, lightheadedness, and syncope. This medicine can cause cardiomyopathy, inform your physician of any signs or symptoms of heart failure.
Precautions when taking Tagrisso osimertinib
Tagrisso Osimertinib is unsafe for pregnancy, and effective contraceptive methods must be discussed with the doctor while taking this medication. This medication is not to be taken by people below the age of 18 years. Breastfeeding must be done only after two weeks from the last dose. If you have a history of heart disorders, and eye problems inform your doctor as this condition requires monitoring. Before starting treatment with this medication, report to your doctor about any medication you are taking.
Side Effects Tagrisso osimertinib
The common side effects of Tagrisso Osimertinib are headache, low WBC and platelets, diarrhea, decreased appetite, anemia, rash, muscle and joint pain, nail changes, dry skin, tiredness , cough, inflamed and sore mouth. Other serious side effects of Osimertinib tablets are decreased heart function, irregular heartbeats, breathing difficulty together with a cough or fever, eye problems, anemia, skin lesions.
